The Best Years of Your Life

When I was young, there was no respect for youth.

Now there's no respect for the old.

I missed it both times!

                                Milton Berle (or so he claims)

When you were a teenager, were you ever told, "Enjoy this time, it's the best years of your life?" What a stupid thing to say. Youth is wasted on the young, and for most people, youth is hardly the best years of life.

Ours is a youth-obsessed culture, demanding living in the now with youthful gusto. Who has time for lessons learned and the wisdom that comes with age? Here's one example that only older people know: All this excitement about legalizing marijuana is being fomented by people who know nothing of the exhaustive social and scientific marijuana research conducted in the 1930s and the harmful biological effects in the 1970s.  Older scholars know about this, but younger ones seem woefully uninformed and uninterested in "old" research. Actually, that often applies to old research in all fields.

We are all going to get old, assuming we don't die first. Our friends, relatives, and loved ones are or will get old. As baby boomers retire, older people are coming to dominate the population. Modern medicine and the wide pursuit of healthier living styles have enabled many older people to live longer and remain vigorous and productive in their old age. Yet, in this country and many other Western countries, we shun, neglect, and sometimes abuse the old. This is the theme of a recent blog by the CEO of a medical products company, Sue Chen.

Chen contends that as people age, others lose interest in engaging with them. A recent National Research Council study indicated that older adults are stigmatized as a group. Older people are treated like old people in social groups and in the workplace. Less is expected of seniors. Seniors in turn expect less of themselves. Chen asserts that younger people shun the elderly and don't want to think about aging because they are afraid of their own impending aging. They know that older people become more socially isolated and that the loneliness is magnified when divorce or death causes the loss of a spouse. Children are unintentionally conditioned to have negative bias about older people. Young families often shut out older parents, aunts, and uncles. We seem to have abandoned the "extended family" concept that was so wholesomely dominant only a few decades ago.

Fear of further aging and being sick and lonely grows with each passing year. Fear of aging is unwarranted, at least for healthy seniors with sufficient retirement income. Actually, one's later years can be the best years of life. Helen Hayes, at age 73, said "The hardest years are between 10 and 70." Paul Meyer, upon reaching 70, claimed that "Life begins at 70." By that time we all have accumulated a "rich reserve" of life experiences and lessons learned. He tries to do all the things he has always done. He points out some of the many advantages of old age, such as people expecting less of you. What you do accomplish makes a bigger impression because it isn't expected. At 70 you have more choices. You can act your age or act young. You can do things you didn't have time for in the past, particularly "smelling the roses." You can take naps without feeling guilty. You feel less guilty about the way you raised your kids, because now they know just how hard raising kids is and are having many of the same difficulties and angst as you did. Time becomes precious, because it is running out. You therefore spend it more wisely. You don't waste time on harmful emotions or personal animosities.

Now at 81, my experience is consistent with what Hayes and Meyer concluded.  I am, even though semi-retired, more efficient and almost as productive in my profession as when I "retired." Amazingly, I have discovered more free time to work. And now, I get to do what I want to do, not what others want me to do. But the biggest advantage of aging, as I see it, is that older people have typically learned more about how to cope with disappointment and adversity and how to squeeze the sweet and good juice out of life.

In the absence of debilitating sickness, aging can be a great blessing. There are many things people can and should be doing to make the senior years the best years of their lives. These include eating well, exercising frequently and vigorously, constructing a positive emotional attitude, becoming more active in mental and social life, getting frequent medical checkups, and most of all I think, living with an honorable purpose.

To know more about aging well, check out my e-book, Improve Your Memory for a Healthy Brain. Memory Is the Canary in Your Brain's Coal Mine, available at Smashwords.com. My "Improve Learning and Memory" blog is at http://thankyoubain.blogspot.com.

Sources:

http://www.oxfordscholarship.com/view/10.1093/acprof:oso/9780195138931.001.0001/acprof-9780195138931-chapter-4. Accessed Oct. 17, 2015.

Chen, Sue (2015). What you don't know about aging could kill you. http://www.huffingtonpost.com/hippo-reads/what-you-dont-know-about-_9_b_8091512.html

Meyer, Paul J. (2000). Making the rest the best. Chicken Soup for the Golden Soul. Deerfield Beach, Fl.: Health Communications.  p. 480-486.

Behavioral Therapy Erases Bad Memories: Timing Matters

It has taken 50 years, but memory research has finally put it all together to provide practical guidance to reduce forgetting of what we need to remember and promote forgetting of useless or disturbing memories.

I have blogged before about animal studies showing that bad memories can be erased. Bad memories are often created like conditioned reflexes in Pavlov’s dogs. That is, the situational context in which bad things occur act as associational cues that help cement the memory. If the cues are repeatedly present but the bad event is not, the learned associated tends to go away.

But in both animals and humans, this “extinction” as it is called is not really permanent and the bad memories can recur.  

Memory researchers have recently discovered that when a memory is recalled, whether good or bad, there is a short time where it can be modified by new thought or experience, and then it is put back in storage (called “reconsolidation”). When this phenomenon was discovered, it raised the possibility that timing of extinction trials might influence effectiveness of treatments for anxiety. That is, better treatment results might occur if extinction is attempted during the vulnerable reconsolidation stage. In 2009, Joseph LeDoux and his colleagues demonstrated in rodents that timing of extinction trials did in fact influence the erasure of fear memory.  

This modifiable stage provides a way to treat even really bad memories, like post-traumatic stress disorder. When a soldier, for example, recalls a bomb killing a buddy, that terrible memory is subject to modification before it is re-stored. A typical modern treatment for PTSD is to inject an anxiety-reducing drug just before the bad memory is triggered that interferes with reconsolidation of memory. This process may have to be repeated many times before the bad memory is finally gone. Now a new study from the Uppsala University in Sweden has shown that bad memories can be erased without drug.

Investigators created bad memories in human volunteers by giving them an electric shock each time a certain picture was flashed on a computer screen. They repeated this experience 16 times to establish a conditioned fear response. The next day after such training, the subjects were brought back into the test room, and the fear-of-shock memory re-triggered by showing the picture that had been associated with shock. This was repeated eight times without associated shock, as a way to produce extinction. Half of the subjects received their extinction treatments at 10 minutes later in which the fearful stimulus was repeated without any shock. The other half of the subjects were given the same extinction treatment but delayed six hours, when it was presumably too late to interfere with reconsolidation.

To measure the amount of fear evoked by later presentations of the picture, investigators objectively measured the amount of fear, using a skin conductance test that measured essentially how sweaty the palms were. Signs of fear were absent in the group given extinction trials at 10 minutes when reconsolidation was still in progress. But signs of fear persisted in the six-hour group.

To pursue questions about what was happening in the brain, investigators used brain imaging, and particularly noticed activity changes in the amygdala, a structure deep within the brain that is hyperactive in the presence of fear memories. On the third day, all subjects were brought back to the lab and brain scans run when the fearful image was shown. In those subjects in the six-hour group, activity in the amygdala predicted whether signs of fear (skin conductance) would return. No such prediction occurred in the 10-min group. In other words, people who lost their fear memory, as indicated by skin sweating, also lost the signs of the memory in the amygdala. Similar effects were seen in the network of other brain areas linked to the amygdala in the processing of fear memories.

None of this should have been surprising. Back in the 1960s, I and many others conducted studies in animals that showed memory of a learning event depended on what happened shortly after the learning. We knew that this short window of time was vulnerable to other mental events that could prevent memory consolidation. Implications for education were obvious: multi-tasking, for example, introduces mental events that interfere with memory consolidation. But one wonders why it took science 50 years to apply what we knew about consolidation to the treatment of anxiety disorders. The key was the recent discovery that recall of a memory puts it back in the vulnerable position of having to be reconsolidated.

Source:

Agren, T. et al. (2012). Disruption of reconsolidation erases a fear memory trace in the human amygdala. Science. 337 (6101): 1550-1552.